Exposure Centre

Something happened — what is my risk?

If you have had a recent sexual encounter you are concerned about, this guide will help you understand your risk, what action to take, and when to get tested.

Concerned about HIV? PEP must be started within 72 hours.

Post-Exposure Prophylaxis (PEP) is a course of HIV medication that can prevent infection if started promptly after a high-risk exposure. Every hour counts. Go to your nearest A&E or sexual health clinic immediately.

Learn about PEP and HIV exposure

PEP window — time matters

If you had a high-risk HIV exposure, this timeline shows when PEP can be prescribed.

0–24h

Ideal window

Start PEP as soon as possible — within 24 hours gives the best outcomes.

24–48h

Still effective

PEP remains highly effective. Do not delay — seek medical attention today.

48–72h

Last chance

This is the outer boundary. PEP may still be started but should not be delayed further.

After 72h

PEP not available

PEP is not recommended beyond 72 hours. Discuss other options with a clinician.

Risk by type of exposure

These risk levels are generalisations. Individual circumstances, vaccination status, and partner status all affect actual risk.

Unprotected vaginal sex

Moderate-high risk

Vaginal intercourse without a condom carries a meaningful risk of transmission for chlamydia, gonorrhoea, syphilis, herpes, HPV, and — to a lesser degree — HIV.

STIs to consider testing for

ChlamydiaGonorrhoeaSyphilisHerpesHPVHIVTrichomoniasis

When to test

2 weeks minimum for most bacterial STIs; 45 days for HIV 4th gen.

Unprotected anal sex (receptive)

Higher risk

Receptive anal intercourse carries the highest per-act HIV transmission risk of any sexual activity. Risk for gonorrhoea, chlamydia and syphilis is also significant.

STIs to consider testing for

HIVGonorrhoeaChlamydiaSyphilisHerpesHPV

When to test

45 days for HIV (4th gen); 2 weeks for bacterial STIs.

Consider PEP if within 72 hours

Unprotected anal sex (insertive)

Moderate risk

The insertive partner in anal sex has a lower — but not negligible — HIV risk. Risk for gonorrhoea, syphilis and herpes remains relevant.

STIs to consider testing for

HIVGonorrhoeaSyphilisHerpes

When to test

45 days for HIV (4th gen); 2 weeks for bacterial STIs.

Consider PEP if within 72 hours

Unprotected oral sex

Lower risk

Oral sex carries a much lower risk than penetrative sex for most STIs. Gonorrhoea of the throat (pharyngeal gonorrhoea) is the most common concern, alongside herpes and syphilis.

STIs to consider testing for

Gonorrhoea (throat)Herpes (HSV-1)Syphilis

When to test

2 weeks for gonorrhoea; individual assessment for others.

Condom broke or slipped

Moderate risk

A single incident of condom failure is considered a lower-risk event than unprotected sex, but still warrants assessment — particularly if the partner's status is unknown.

STIs to consider testing for

HIVChlamydiaGonorrhoeaSyphilis

When to test

Same as unprotected sex guidance above.

Sex with a known positive partner

Variable — assess individually

Risk depends heavily on the specific infection, whether treatment is in place (e.g. HIV Undetectable = Untransmittable), and protective measures used. Individual assessment is strongly recommended.

STIs to consider testing for

Specific to disclosed infection

When to test

Seek specialist advice promptly.

What to do after a potential exposure

  1. 1

    Assess your HIV risk first

    If the encounter carries a HIV risk and happened within the last 72 hours, your first priority is accessing PEP. Go to A&E or call an emergency sexual health line now.

  2. 2

    Note the timing of the exposure

    Write down the date and approximate time. Many STI tests have a minimum testing window — testing too early produces unreliable results.

  3. 3

    Use our Exposure Checker tool

    Our interactive tool asks structured questions about the encounter and provides a personalised recommendation for testing and timelines.

  4. 4

    Book a sexual health appointment

    Most sexual health clinics offer same-day or next-day appointments for people who have had a recent risk exposure. You do not need a GP referral.

  5. 5

    Avoid further unprotected sex until tested

    If an infection is present, you may be infectious even before symptoms appear. Protecting partners until you have a result is important.

Get a personalised exposure assessment

Answer a few questions and we will guide you through your next steps.

Use Exposure Checker